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KMID : 0361120160300040190
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Korean Journal of Transplantation
2016 Volume.30 No. 4 p.190 ~ p.193
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Calcineurin Inhibitor Induced Multiple Infarctions
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Jeong Hae-Bong
Kim Jeong-Min
Yoo Il-Han
Bae Jae-Han
Kwon Oh-Sang
Park Kwang-Yeol
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Abstract
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Tacrolimus is the most commonly used immunosuppressant after kidney transplantation. Here, we report a patient with multiple cerebral infarctions during tacrolimus treatment after kidney transplantation. A 54-year-old female was admitted due to sudden onset right leg weakness. Brain magnetic resonance imaging (MRI) showed multiple acute infarctions but normal vasculature. Evaluations of cardiac embolism were unremarkable. After 8 months, her weakness progressed and follow-up brain MRI showed additional multiple infarctions. We changed here medication from tacrolimus to mycophenolate mofetil, and her symptoms improved gradually.
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KEYWORD
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Tacrolimus, Acute cerebral infarction, Kidney transplantation
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